Early MMR Vaccination of Infants

Due to anticipated ongoing community transmission, NCDHHS now recommends that clinicians consider early vaccination for infants 6 – 11 months of age residing or spending time in the Charlotte Metropolitan area, including Mecklenburg, Cabarrus, Gaston, Iredell, Lincoln, Rowan and Union Counties.

  • Additional counties where early vaccination may be considered will be posted in the Measles Resources for Health Care Providers page as the outbreak evolves.
  • Early vaccination should also be considered for infants who will be spending time in other areas where measles transmission is occurring, which currently includes Upstate SC.
  • We encourage pediatricians and family physicians to identify infants in your care who qualify for early MMR vaccination under this updated guidance and notify their parents and guardians of the recommendation.
  • While Mecklenburg County Public Health is available to provide early vaccination, families are encouraged to schedule appointments with their primary care provider for timely access and consultation.
  • Assistance with scheduling appointments at the Mecklenburg County Immunization Clinics is available by calling 980-314-9400. Appointments are encouraged, but walk-ins are welcome.

When you are discussing the option of an early MMR dose with families, please inform them of the following information:

  •  MMR in infants less than 12 months of age is an “extra” dose. All infants vaccinated prior to 12 months of age will still need to receive two additional doses of MMR after 12 months of age.
  • There is some evidence that infants under 12 months of age may not develop as high a level of protection and may have faster waning of immunity compared to children who receive their first dose of MMR at 12 months of age. This should be balanced against the likelihood of exposure and potential for severe sequelae from measles infection. Longer term evaluation of sustained immune response into adulthood after an additional early MMR vaccine is unclear and needs further study.
  • Risk for severe sequelae from measles infection is highest in infants <12 months of age, including pneumonia, encephalitis, and subacute sclerosing panencephalitis (SSPE).
  • MMR vaccine can cause fever and/or measles-like rash, usually 6-12 days following vaccination.

Vaccines for Children (VFC)-supplied doses can be used for early vaccination in VFC-eligible children. MMRV is contraindicated and cannot be used for the early MMR vaccine for infants aged 6-11 months. Commercial insurance is expected to cover the cost of early MMR vaccination of infants.

Bonnie Coyle, MD, MS, Mecklenburg County Medical Director

Kimberly Scott, DrPH, MPH, Interim Health Director